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An article published on The American Journal on Addictions stated that women that are pregnant who were enslaved by opioids were strongly thinking about antagonist treatment, especially one which involves the use of naltrexone to combat their drug abuse disorder. Using two separate drugs to shed pounds can be very effective you will find combinations in front of the FDA now awaiting approval. When dealing with weight loss and the individuals who go through it one should err to the side of caution and allow FDA do its job and demand some research be done in order that the public understands the side effects and dangers of the medications before we drive them. Keep in mind that drug companies come in business to generate income and that they would say almost anything to keep people on their own medications. Researchers found that participants taking this drug to get a year, dropped excess weight within 4 weeks and have kept the extra weight off through the 56 weeks from the study. Contrave is a combination in the drugs naltrexone and bupropion, which seems to reflect a brand new trend of weight-loss drugs that are made up of many active ingredient, that might make them more effective and safer. Combo-pilling may be the newest fad or in addition to this the newest ahead under scrutiny and thus it is just more publicly known although in the past, comb-pilling to lose weight has been around since the eighties. The biggest reason that utilizing a combination of pills is starting to become popular is the fact that since right now there are no long term prescription weight loss supplements that have been licensed by the FDA apart from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications and some of the combinations are actually rejected or have yet to be licensed by the FDA. Seizures certainly are a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug may also raise blood pressure and heartrate, and must not be used in people who have a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise blood pressure and heartrate and must 't be used in patients with uncontrolled high blood pressure, in addition to by anyone with heart-related and cerebrovascular (blood vessel dysfunction impacting your brain) disease. Patients using a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert physicians and patients for the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stop smoking. New UCLA study on smokers with mental, drug, and alcohol problems