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Contrave is looking very promising for all those seeking a diet pill that works well. The U.S. Food and Drug Administration reviewed Contrave on December 7, and approved the drug 13-7, stating the benefit of the drug outweighs the chance of a possible rise in blood pressure. Using two separate drugs to shed pounds can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with weight-loss and the people that go through it you ought to err assisting caution and allow the FDA do its job and demand some research be done so the public recognizes the side effects and dangers of the medications before we drive them. Keep in mind that drug companies come in business to make money and that they would say everything to keep people on their medications. Researchers discovered that participants investing in this drug to get a year, lost weight within 4 weeks and have kept the body weight off throughout the 56 weeks with the study. Contrave is often a combination of the drugs naltrexone and bupropion, which seems to reflect a whole new trend of weight-loss drugs which are made up of multiple active ingredient, which might make them more effective and safer. Combo-pilling is the newest fad or even better the newest into the future under scrutiny and so it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that utilizing a combination of pills is starting to become popular will be the fact that by right now there aren't long term prescription diet pills that have been approved by the FDA besides orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications however some of the combinations happen to be rejected or have yet to be authorized by the FDA. Seizures are a side effect with Contrave and must not be taken in those with seizure disorders. The drug also can raise hypertension and heartbeat, and mustn't be used in people with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise hypertension and heartrate and must not used in patients with uncontrolled high blood pressure, along with by you aren't heart-related and cerebrovascular (circulation system dysfunction impacting the brain) disease. Patients which has a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes which has a boxed warning to alert physicians and patients for the increased chance of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for quitting smoking. "This will be the first drug I'm conscious of that targets both the appetite and reward centres in the brain," he explained.